This manual is intended to provide a technical resource for bridge and geotechnical engineers responsible for seismic analysis and design of transportation geotechnical features and structures such as soil and rock slopes, earth embankments, retaining structures and buried structures and structural foundations including shallow and deep foundations and abutments. Topics include earthquake fundamentals and engineering seismology, seismic hazard analysis, ground motion characterization, site characterization, site-specific seismic site response analysis, geotechnical hazards including liquefaction, slope instability, and seismic settlement, and soil-foundation-structure interaction are included.