In order to reveal the sismotectonic characteristics of eastern Mediterranean, it is necessary to fully describe the main four plates in the region, namely, Eurasia, Anatolia, Africa and Arabic plates and their movements. There are three main centers in the region which form the highest level of earthquake effectiveness. These are the Hellenic trench with subduction zone (Crete-Rhodes as center), Cyprus with surrunding regions, and Misis, Ecemi faults in Anatolia, Death Sea fault in the East Mediterranean